Formulation of self-nanoemulsifying drug delivery systems containing monoacyl phosphatidylcholine and Kolliphor® RH40 using experimental design

Formulation Design and Development of Self-Nanoemulsifying Drug Delivery Systems Containing a Hydrophobic Selective β1-Adrenoreceptor Blocker

The present work was aimed to design and develop self-nanoemulsifying drug delivery systems (SNEDDS) with the objective to overcome the problems associated with the delivery of talinolol, a hydrophobic and poorly bioavailable drugs having pH dependant solubility. The solubility of talinolol in various oils, surfactants, cosurfactants and aqueous phases were determined to identify and select the...

formulation design and development of self-nanoemulsifying drug delivery systems containing a hydrophobic selective β1-adrenoreceptor blocker

the present work was aimed to design and develop self-nanoemulsifying drug delivery systems (snedds) with the objective to overcome the problems associated with the delivery of talinolol, a hydrophobic and poorly bioavailable drugs having ph dependant solubility. the solubility of talinolol in various oils, surfactants, cosurfactants and aqueous phases were determined to identify and select the...

development and optimization of sirolimus self nanoemulsifying drug delivery systems containing bioavailability enhancers

Formulation Design and In vitro Evaluation of Berberine- Loaded Self-Nanoemulsifying Drug Delivery System

Purpose: To improve the oral bioavailability of berberine using a new self-nanoemulsifying drug delivery system (SNEDDS). Methods: Berberine SNEDDS was designed using solubility studies and phase diagram construction. A series of tests were carried out to study the effect of oil content, dilution, and drug loading on particle size. The morphology of the nanoemulsion was examined with a transmis...

Self-Nanoemulsifying Drug Delivery Systems Containing Plantago lanceolata-An Assessment of Their Antioxidant and Antiinflammatory Effects.

The most important components of Plantago lanceolata L. leaves are catalpol, aucubin, and acteoside (=verbascoside). These bioactive compounds possess different pharmacological effects: anti-inflammatory, antioxidant, antineoplastic, and hepatoprotective. The aim of this study was to protect Plantago lanceolata extract from hydrolysis and to improve its antioxidant effect using self-nano-emulsi...